May 23rd, 2012 | Category: Computing, Information processing, Media coverage, Papers, Synthetic Biology | Leave a comment

Data storage in living cells

There’s a lot of interest (including at the Beeb) in a new paper from Drew Endy published in PNAS: rewritable digital data storage in live cells via engineered control of recombination directionality.

May 17th, 2012 | Category: Ethics, Papers, Synthetic Biology | Leave a comment

Synthetic ecology and the SynBio landscape

The 4th Domain will be a little quiet over the next few months, mainly due to the upcoming iGEM competition.   Follow the link to see how we are doing. In the meantime there are two papers I would like to draw your attention to.

April 27th, 2012 | Category: Metabolic engineering, Papers, Synthetic Biology | Leave a comment

SynBio Smörgåsbord

There have been a number of interesting stories recently that I have been meaning to write about, but time has got the better of me. There is a growing list of ‘draft’ posts at The 4th Domain, so I thought I would roll them all into one post

April 17th, 2012 | Category: Papers, Synthetic Biology | Leave a comment

Genetic switchboard for synthetic biology applications

A very short post to say that there is a new paper in PNAS that some might find interesting: Genetic switchboard for synthetic biology applications.

April 12th, 2012 | Category: Papers, Synthetic Biology | 2 comments

Expressing bacterial operons in plants

One of the advantages of working with bacteria is that genes can be clustered together under control of a single promoter (known as an operon). Multiple protein products can therefore be generated from a single messenger RNA strand (the mRNA is said to be polycistronic (Fig. 1)).