March 11th, 2015 | Category: Mathematics, Seminars | Leave a comment

Understanding and Engineering Biological Complexity

This summer, myself, John Love and Markus Gershater (Synthace) are organising a session at the SEB AGM in Prague. The session is called Understanding and Engineering Biological Complexity. More information can be found on the SEB website. Confirmed speakers include Rachel Haurwitz (Caribou Bioscience), Phil Ramsey (University of New Hampshire), Claes Gustafsson (DNA2.0) and Srividya […]

January 12th, 2015 | Category: Fungi, Metabolic engineering, Microbiology, Organisms, Saccharomyces | Leave a comment

BBSRC PhD iCASE available (start Sep 2015)

I have a BBSRC-funded iCASE PhD available with Biosyntha Technologies. Project Description: Global climate change and finite fuel reserves are driving interest in biologically derived fuel molecules. Such molecules include isoprenoid-derived biofuels, short chain alcohols, polyketide-derived fuels, alkanes and alkenes. As naturally produced however, these potential biofuel molecules may not match the standards, or have the […]

January 12th, 2015 | Category: iGEM, Synthetic Biology | Leave a comment

Exeter iGEM 2015 Recruitment

It’s that time of year again… This year the University of Exeter will again be entering a team into the International Genetically Engineered Machines (iGEM) Competition: Once again we will be assembling a multidisciplinary team of undergraduate researchers. Previous teams (here, here and here) have included Physicists, Engineers, Mathematicians, Computer Scientists, Psychologists and of course […]

December 20th, 2013 | Category: Mathematics, Metabolic engineering, Papers | Leave a comment

Multi-enzyme pathway engineering

Engineering metabolic pathways, whether for pharmaceuticals or fuels, involves many trade-offs. Flux imbalances (for example where flux through the first step exceeds flux through the second) can lead to the accumulation of toxic intermediates. Moreover, expressing heterologous proteins beyond that which is necessary can place a burden upon the cell for protein, rather than product, […]

November 29th, 2013 | Category: Metabolic engineering, Protein design, Synthetic Biology | Leave a comment

Potential PhD Position: Biosynthetic Lego: Building antibiotic assembly lines from first principles

There is a PhD position available with Paul Race at Bristol that I will be co-supervising (subject to securing the funding). If successful this will be funded through the South West Doctoral Training Partnership. The PhD will be a fully-funded, four-year programme designed to provide training in cutting edge world-class bioscience and food security research skills. […]

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