December 20th, 2013 | Category: Mathematics, Metabolic engineering, Papers | Leave a comment

Multi-enzyme pathway engineering

Engineering metabolic pathways, whether for pharmaceuticals or fuels, involves many trade-offs. Flux imbalances (for example where flux through the first step exceeds flux through the second) can lead to the accumulation of toxic intermediates. Moreover, expressing heterologous proteins beyond that which is necessary can place a burden upon the cell for protein, rather than product, […]

November 29th, 2013 | Category: Metabolic engineering, Protein design, Synthetic Biology | Leave a comment

Potential PhD Position: Biosynthetic Lego: Building antibiotic assembly lines from first principles

There is a PhD position available with Paul Race at Bristol that I will be co-supervising (subject to securing the funding). If successful this will be funded through the South West Doctoral Training Partnership. The PhD will be a fully-funded, four-year programme designed to provide training in cutting edge world-class bioscience and food security research skills. […]

October 25th, 2013 | Category: E. coli, Media coverage, Metabolic engineering, Video | Leave a comment

German Diesel and Other News

For German coverage of our biofuels paper, look no further than 3sat. The article starts at 22mins and features interviews and cameos from many in the mezz. lab. Keep your eyes pealed for a stealth technician around the 23.40min mark. Further good news is a nomination for a University of Exeter Impact Awards in the ‘Outstanding impact […]

December 3rd, 2012 | Category: Mathematics, Metabolic engineering, Microbiology | Leave a comment

Synthetic Biology PhD positions at Exeter

Any recent graduates or undergraduates in their final year looking for PhD positions in synthetic biology, take note: there are six synthetic biology PhD studentships available at the University of Exeter looking at biomethane-producing microbial communities (BMCs).

June 22nd, 2012 | Category: Arabidopsis, iGEM, Metabolic engineering, Papers | Leave a comment

Harvard iGEM 2010

The iGEM team from Harvard 2010, and their iGarden have found their way to publication in the Journal of Biological Engineering. Their new paper, “A BioBrick compatible strategy for genetic modification of plants“

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