Final year PGR Narima Eerqing recently gave an oral presentation at Conference on Lasers and Electro-Optics (CLEO) 2022 on ”Comparing Individual DNA Transient Hybridization Kinetics Using DNA-PAINT and Optoplasmonic Sensing Techniques”.
Narima explains the findings of his work:
Very happy to present my work at the Conference on Lasers and Electro-Optics (CLEO) 2022; this is the first in-person conference for me after almost 3 years! CLEO conference is a showcase for leading research and applications in a number of fields, from optical imaging to advanced manufacturing, silicon photonics and the autonomous vehicles industry. It is a great pleasure to encounter many brilliant ideas and talk to scientists across different laser science and photonics research. The work I presented is entitled: ”Comparing Individual DNA Transient Hybridization Kinetics Using DNA-PAINT and Optoplasmonic Sensing Techniques”, where I reported a comparison of two photonic techniques for single-molecule sensing: fluorescence nanoscopy and optoplasmonic sensing. I demonstrated that DNA dissociation is not significantly altered by the fluorescent labels and that DNA association is affected by geometric factors in the two techniques. These findings open the door to exploiting plasmonic sensing and fluorescence nanoscopy in a complementary fashion, which will aid in building more powerful sensors and uncovering the intricate effects that influence the behavior of single molecules.